Lisa Bonner

Assistant Professor of Chemistry

James Center for Molecular and Life Sciences 138


  • Ph.D., Medicinal Chemistry and Molecular Pharmacology, Purdue University
  • B.S., Chemistry and Biochemistry, summa cum laude, Loyola College, Maryland

Research Interests

Her research concerns the design and synthesis of molecules with a specific biological purpose: to modulate how dopamine works in the brain. Additionally working to improve organic chemistry laboratories and integrate polymer chemistry into the organic chemistry curriculum. Through the tutoring program she is assessing the efforts of additional practice problems on exam grades in both general and organic chemistry courses.

Courses Taught

  • CH 221 Organic Chemistry I
  • CH 222 Organic Chemistry II
  • CH 122 General Chemistry II
  • HP 220 Honors Seminar: Multidisciplinary Perspectives on Sex and Gender

Select Publications

  • Juncosa, JI; Hansen, M; Bonner, LA; Cueva, JP; Maglathlin, R; McCorvy, J; Marona-Lewicka, D; Lill, MA; Nichols, DE. Extensive rigid analogue design maps the binding conformation of potent N-benzylphenethylamine 5-HT2A serotonin receptor agonist ligands. ACS Chemical Neuroscience, 4: 96-109, 2013.
  • Chemel, BR; Bonner, LA; Watts, VJ; Nichols, DE. Ligand-Specific Roles for Transmembrane 5 Serine Residues in the Binding and Efficacy of Dopamine D1 Receptor Catechol Agonists. Molecular Pharmacology, 81: 729-738, 2012.
  • Bonner, LA; Laban, U; Chemel, BR; Juncosa, JI; Lill, MA; Watts, VJ; Nichols, DE. Mapping the Catechol Binding Site in Dopamine D1 Receptors: Synthesis and Evaluation of Two Parallel Series of Bicyclic Dopamine Analogues. ChemMedChem. 6: 1024-1040, 2011.
  • Bonner, LA; Chemel, BR; Watts, VJ; Nichols, DE. Facile Synthesis of Octahydrobenzo[h]isoquinolines: Novel and Highly Potent D1 Dopamine Agonists. Bioorganic and Medicinal Chemistry. 18: 6763-6770, 2010.
  • Bonner, LA; Frescas, SP; Nichols, DE. A Facile Method for the Preparation of Pure cis-2,4-pentanediol. Synthetic Communications, 34 (15): 2767-2771, 2004.