Joseph Larkin

Professor of Chemistry

James Center for Molecular and Life Sciences 085


  • Ph.D., Chemistry, University of Georgia
  • B.Sc., Jefferson University

Research Interests

Computational modeling of boron-containing small molecules as saccharide sensors and cancer treatments

Courses Taught

  • CH 121 General Chemistry I
  • CH 122 General Chemistry II
  • CH 321 Physical Chemistry I
  • CH 322/324 Physical Chemistry II

Select Publications

  • J.D. Larkin and C.W. Bock; A Comparison of the Structure and Bonding in the Donor-Acceptor Complexes H3N→BR(OH)2 and H3N→BRH(OH) (R = H; NH2, OH, and F): A Computational Investigation. Struct Chem, 2018.
  • B.M. Chapin, P. Metola, S.L. Vankayala, H.L. Woodcock, T.J. Mooibroek, V.M. Lynch, J.D. Larkin, E.V. Anslyn; “Disaggregation is a Mechanism for Emission Turn-On of ortho-Aminomethylphenylboronic Acid-Based Saccharide Sensors” JACS, 2017, 139, 5568.
  • Venkayala; F. Kearns; J.D. Larkin; B. Baker; H.L. Woodcock; “Elucidating the Chemical Defense Mechanism of Antarctic Sea Sponges: A Computational Study” Journal of Chemical Information and Modeling, 2017, 71, 104.
  • Rao; Larkin, J.D.; Bock, C.W; “Monosubstituted Phenylboronic Acids, R–B(OH)2(R = C6H5, C6H4CH3, C6H4NH2, C6H4OH, and C6H4F): A Computational Investigation”  Structural Chemistry. 2017, 28, 945.
  • N. Rao; Larkin, J.D.; Bock, C.W; “A Comparison of the Bonding in the Aliphatic Boronic Acids R–B(OH)2 and H3N→BR(OH)2 (R = H; NH2, OH, and F) and Their Borinic Acid Analogs: A Computational Investigation”  Structural Chemistry. 2016, 27, 1081.