Jalisa H. Ferguson

Assistant Professor of Chemistry

James Center for Molecular and Life Sciences 136


  • Ph.D. in Organic Chemistry, Georgia State University, 2017
  • B.S. in Chemistry, Mercer University, 2010

Research Interests

I am interested in using computer-aided drug design and other medicinal chemistry approaches to identify inhibitors of proteins with implications in cancer and other diseases. I, along with students in my group, intend to design potential inhibitors, synthesize those small molecules, and then conduct biological testing in vitro (in cells). Additionally, we’ll aim to target those drugs selectively toward cancer cells using hypoxia targeting strategies.

Courses Taught

  • CH 221 Organic Chemistry 1

Select Publications

  • Ferguson, JH; De los Santos, ZA; Devi, SN; Kaluz, S; Van Meir EG; Zingales, SK; Wang, B. Design and synthesis of benzopyran-based inhibitors of the hypoxia-inducible factor-1 pathway with improved water solubility. J Enzyme Inhib Med Chem. 2017, 32, 992-1001.
  • Ferguson, JH; De los Santos, ZA; Devi, SN; Van Meir EG; Zingales, SK; Wang, B. Examining the structure-activity relationship of benzopyran-based inhibitors of the hypoxia inducible factor-1 pathway. Bioorg Med Chem Lett. 2017, 27, 1731-1736.
  • Draganov, A; Wang, D; Holmes, J; Ji, K; Wang, B. “Synthetic Receptors for Carbohydrates.” In Bradley Smith (ed.), Synthetic Receptors for Biomolecules: Design Principles and Applications. Chapter 5, 2015, 177-203.
  • Draganov, A; Wang, K; Holmes, J; Damera, K; Wang, D; Dai, C; Wang, B. Click with a Handle: A Neighboring Group-assisted Click Reaction that Allows Ready Secondary Functionalization. Chem Commun. 2015, 51, 15180-15183.

Banner photo (top): Credit AXURIT 1